Temporary salt crystals may provide a permanent solution to Alzheimer's

(Osaka University) Researchers at Osaka University have demonstrated that precipitation of a salt crystal occurs even at concentrations much lower than its solubility due to local density fluctuation and this repeated precipitation-dissolution of salt crystals significantly accelerates the production of neurotoxic aggregates of amyloid-β peptides. These results help elucidate the protein aggregation mechanism and the pathogenesis of Alzheimer's disease.